Screening Elderly Patients for Weaning

PHASE2CompletedINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

December 31, 2015

Study Completion Date

December 31, 2015

Conditions
Critically Ill
Interventions
PROCEDURE

Once daily screening

In the 'once daily screening arm', RTs will screen invasively ventilated patients between approximately 06:00 - 08:00 hours daily. To pass the 'readiness to wean screen' and undergo an SBT, specific criteria must be met. The initial SBT will be 30-120 minutes in duration and may be conducted with any one of the following techniques: T-piece, continuous positive airway pressure (CPAP) less than or equal to 5 cm H2O or PS less than or equal to 8 cm H2O with PEEP less than or equal to 5 - 10 cm H2O. Higher levels of PEEP (8-10 cm H2O) will be permitted (and recorded) to allow for clinician discretion in conducting SBTs in specific patients (e.g., obese, chronic obstructive pulmonary disease) and use of different humidification strategies. Each centre will be asked to choose one technique to be used for patients enrolled at their centre.

PROCEDURE

At least twice daily screening

In the 'at least twice daily' screening arm patients will be screened at a minimum between approximately 6:00-8:00 hours and 13:00-15:00 hours daily. To pass the 'readiness to wean screen' and undergo an SBT, specific criteria must be met. The initial SBT will be conducted in the same manner as in the once daily screening arm. The subsequent SBTs will be 30 -120 minutes in duration and may be conducted with any one of the following techniques: T-piece, CPAP \< to 5 cm H2 O or PS \< 8 cm H2 O with PEEP \< 5 - 10 cm H2O. Higher levels of PEEP (8-10 cm H2O) will be permitted (and recorded) to allow for clinician discretion in conducting SBTs in specific patients (e.g., obese, chronic obstructive pulmonary disease) and with the use of different humidification strategies. Each centre will be asked to choose one technique for all patients enrolled at their centre.

Trial Locations (8)

Unknown

St. Paul's Hospital, Vancouver

Hamilton General Hospital, Hamilton

St Joseph's Hospital, Hamilton

Ottawa General Hospital, Ottawa

Mount Sinai Hospital, Toronto

St. Michael's Hospital, Toronto

Universite Hopitalier de Sherbrooke, Sherbrooke

H2X 3J4

Hôpital Saint-Luc, Montreal

All Listed Sponsors
lead

Unity Health Toronto

OTHER

NCT02243449 - Screening Elderly Patients for Weaning | Biotech Hunter | Biotech Hunter