Topiramate-Phentermine Combinations for Cocaine Dependence

PHASE1CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

September 30, 2014

Primary Completion Date

September 30, 2019

Study Completion Date

September 30, 2019

Conditions
Cocaine Use Disorder
Interventions
DRUG

Cocaine

The pharmacodynamic effects of cocaine will be determined during maintenance on placebo and topiramate.

DRUG

Placebo

The pharmacodynamic effects of placebo will be determined during maintenance on placebo and topiramate.

DRUG

Phentermine

The pharmacodynamic effects of phentermine maintenance will be determined during maintenance on placebo and topiramate.

DRUG

Topiramate

The pharmacodynamic effects of chronic topiramate will be determined.

Trial Locations (1)

40536

University of Kentucky Medical Center, Lexington

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

University of Kentucky

OTHER

NCT02239913 - Topiramate-Phentermine Combinations for Cocaine Dependence | Biotech Hunter | Biotech Hunter