Brain Inflammation and Function in Alcoholism

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

February 19, 2015

Primary Completion Date

August 16, 2021

Study Completion Date

August 16, 2021

Conditions
Alcohol Use Disorder (AUD)
Interventions
OTHER

connectivity

Magnetic resonance imaging (MRI) scans will be done to assess brain structure, functional reactivity and functional connectivity.

DRUG

neuroinflammation

The use of \[11C\]PBR28 will allow us to assess for the first time in vivo if there is neuroinflammation in the brain of alcoholics. It will also allow us to assess if it recovers with alcohol detoxification.

OTHER

neurofunction

To assess regional brain glucose metabolism.

Trial Locations (1)

20892

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

NCT02233868 - Brain Inflammation and Function in Alcoholism | Biotech Hunter | Biotech Hunter