Drug-Drug Interaction Study With AZD9291 and Omeprazole in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

September 30, 2014

Primary Completion Date

January 31, 2015

Study Completion Date

January 31, 2015

Conditions
Healthy Volunteer
Interventions
PROCEDURE

Pharmacokinetic sampling - AZD9291

Blood sampling to measure AZD9291

DRUG

AZD9291 tablet dosing

AZD9291 80mg tablet taken on Day 5 in Period 1 and Day 1 in Period 2.

DRUG

Omeprazole tablet dosing

Omeprzole taken from Days 1 to 5 in Period 1.

PROCEDURE

Pharmacokinetic sampling - AZ5140 and AZ7550

Blood samples to measure levels of AZ5140 and AZ7550

Trial Locations (2)

Unknown

Research Site, Overland Park

Research Site, Minneapolis

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY