SBRT for Hepatocellular Carcinoma Patients With Partial Response to TACE

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

August 31, 2014

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Carcinoma, Hepatocellular
Interventions
RADIATION

SBRT

"SBRT will be prescribed according to the Radiation Therapy Oncology Group (RTOG) 1112 protocol using Mean Liver Dose (MLD) as parameter. MLD will be calculated using Liver minus Gross Tumor Volume (GTV). Prescription dose will follow the scheme below:~Prescription dose(Gy) / (MLD) (Gy)~50 / 13~45 / 15~40 / 15~35 / 15.5~30 / 16~27.5 / 17~If the dose constraints cannot be met, prescription will be according to the level immediately bellow.~Treatment will be delivered in 5 fractions in consecutive working days"

Trial Locations (1)

01246000

Instituto do Cancer do Estado de Sao Paulo, Hospital das Clinicas da Faculdade de Medicina da USP, São Paulo

All Listed Sponsors
lead

University of Sao Paulo

OTHER