Cardioprotection by Sevoflurane Preconditioning in Noncardiac Thoracic Surgery

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

September 30, 2012

Primary Completion Date

August 31, 2013

Study Completion Date

September 30, 2013

Conditions
High Sensitive Troponin T Release
Interventions
DRUG

Sevoflurane

Anaesthesia is induced (1-2 mg/kg) and maintained (5-7 mg/kg/h) with propofol and remifentanil (1 µg/kg and 0,2-0,4 µg/kg/min). After induction of anesthesia the propofol infusion is stopped and patients receive 1 MAC Sevoflurane over 30 min. Then the propofol infusion is restarted and Sevoflurane is washed out.

DRUG

TIVA

Anaesthesia is induced (1-2 mg/kg) and maintained (5-7 mg/kg/h) with propofol and remifentanil (1 µg/kg and 0,2-0,4 µg/kg/min).

Trial Locations (1)

65199

Dr Horst Schmidt Klinik, Wiesbaden

All Listed Sponsors
lead

Dr. Horst Schmidt Klinik GmbH

INDUSTRY

NCT02217319 - Cardioprotection by Sevoflurane Preconditioning in Noncardiac Thoracic Surgery | Biotech Hunter | Biotech Hunter