H7N9 Mix and Match With MF59 in Healthy Elderly Persons

PHASE2CompletedINTERVENTIONAL
Enrollment

479

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

July 31, 2016

Study Completion Date

July 31, 2016

Conditions
Avian Influenza
Interventions
DRUG

MF59

Microfluoridized adjuvant 59 (MF59) is an oil-in-water emulsion. Group 1-6 receive 3.75 mcg, 7.5 mcg and 15 mcg.

BIOLOGICAL

Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013

Monovalent inactivated split influenza virus vaccine made with HA antigen derived from the influenza A/Shanghai/2/2013 virus. Monovalent influenza A/H7N9 virus vaccine. Group 1-6 receive 3.75 mcg, 7.5 mcg and 15 mcg.

Trial Locations (10)

27704

Duke Human Vaccine Institute - Duke Clinical Vaccine Unit, Durham

30030-1705

Emory Vaccine Center - The Hope Clinic, Decatur

52242-2600

University of Iowa - Vaccine Research and Education Unit, Iowa City

21201-1509

University of Maryland School of Medicine - Center for Vaccine Development - Baltimore, Baltimore

63104-1015

Saint Louis University - Center for Vaccine Development, St Louis

45229-3026

Cincinnati Children's Hospital Medical Center - Infectious Diseases, Cincinnati

37232-0011

Vanderbilt University Medical Center - Vanderbilt Institute for Clinical and Translational Research - Clinical Research Center (VICTR-CRC), Nashville

77555-1119

University of Texas Medical Branch - Sealy Center for Vaccine Development - Clinical Trials Group, Galveston

77030-3411

Baylor College of Medicine - Molecular Virology and Microbiology, Houston

98101-1466

Group Health Research Institute - Seattle - Vaccines and Infectious Diseases, Seattle

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT02213354 - H7N9 Mix and Match With MF59 in Healthy Elderly Persons | Biotech Hunter | Biotech Hunter