Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

September 30, 2014

Primary Completion Date

June 25, 2019

Study Completion Date

June 25, 2019

Conditions
StrokeMotor Function
Interventions
DEVICE

Active Repetitive Transcranial Magnetic Stimulation (rTMS)

Subjects will undergo active low-frequency rTMS (1Hz continuous). Each session will last 20 minutes and will be conducted at 100% of the motor threshold.

DRUG

Fluoxetine

Subjects will receive active fluoxetine (20mg) and take orally consecutively for 90 days.

DEVICE

Sham repetitive transcranial magnetic stimulation (rTMS)

Subjects will undergo sham low-frequency rTMS (using sham coil). This session will last 20 minutes, just as the active session would, however, no magnetic pulses will be delivered.

DRUG

Placebo Fluoxetine

Subject will receive placebo fluoxetine (sugar pills) and will take orally consecutively for 90 days.

Trial Locations (1)

02129

Spaulding Rehabilitation Hospital, Charlestown

All Listed Sponsors
lead

Spaulding Rehabilitation Hospital

OTHER

NCT02208466 - Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients | Biotech Hunter | Biotech Hunter