A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis

PHASE3CompletedINTERVENTIONAL
Enrollment

837

Participants

Timeline

Start Date

November 26, 2014

Primary Completion Date

September 29, 2015

Study Completion Date

June 17, 2020

Conditions
Psoriasis
Interventions
DRUG

Guselkumab 100 mg

100 mg by subcutaneous injection at Weeks 0, 4 and q8w thereafter through Week 252 (Group 1). 100 mg by subcutaneous injection at Weeks 16, 20 and q8w thereafter through Week 252 (Group II). 100 mg by subcutaneous injection at Week 52 and q8w thereafter through Week 252 (Group III).

DRUG

Placebo for guselkumab

Subcutaneous injections to maintain the blind.

DRUG

Adalimumab

80 mg by subcutaneous injection at Week 0, then 40 mg at Week 1 and every 2 weeks (q2w) thereafter through Week 47.

DRUG

Placebo for adalimumab

Subcutaneous injections to maintain the blind.

Trial Locations (97)

Unknown

Los Angeles

San Diego

San Francisco

Aurora

Farmington

Clearwater

Coral Gables

Ocala

Alpharetta

Rolling Meadows

Plainfield

Boston

Troy

New Brighton

St Louis

East Windsor

Albuquerque

Portland

Pittsburgh

Johnston

Arlington

Austin

Dallas

San Antonio

Webster

Norfolk

Darlinghurst

East Melbourne

Hectorville

Liverpool

Melbourne

Westmead

Woden

Woolloongabba

Calgary

Edmonton

Vancouver

St. John's

Halifax

Ajax

London

North Bay

Peterborough

Montreal

Berlin

Bonn

Dresden

Essen

Frankfurt am Main

Gera

Hamburg

Kiel

Lübeck

Mahlow

Münster

Tübingen

Budapest

Debrecen

Kaposvár

Kecskemét

Pécs

Szeged

Bialystok

Bydgoszcz

Lodz

Olsztyn

Warsaw

Wroclaw

Kirov

Krasnodar

Lipetsk

Moscow

Rostov-on-Don

Ryazan

Saint Petersburg

Stavropol

Ulyanovsk

Yekaterinburg

Bundang

Busan

Daejeon

Seoul

Suwon

Barakaldo

Barcelona

Córdoba

Madrid

Manises

Palma de Mallorca

Salamanca

San Sebastián de los Reyes

Valencia

Kaohsiung City

Taichung

Tainan City

Taipei

Taoyuan District

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT02207231 - A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis | Biotech Hunter | Biotech Hunter