The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia

PHASE4CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2016

Conditions
Propofol-anaesthesia Via Target-controlled Infusion
Interventions
PROCEDURE

Partial pressure of CO2 at the end of an exhaled breath

Three previously defined EtCO2 levels (partial pressure of CO2 at the end of an exhaled breath) were adjusted during anesthesia.

DRUG

Propofol

Propofol is administered to all patients via target-controlled infusion (TCI) to reach 4 mcg/ml constant plasma concentration according to the Schneider model during the course of the narcosis.

Trial Locations (1)

4032

University of Debrecen Medical and Health Science Center Department of Anesthesiology and Intensive Care, Debrecen

All Listed Sponsors
lead

University of Debrecen

OTHER

NCT02203097 - The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia | Biotech Hunter | Biotech Hunter