Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma

PHASE2CompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

August 31, 2019

Study Completion Date

October 31, 2020

Conditions
Low-Grade Glioma
Interventions
DRUG

ORAL VINORELBINE

Orally vinorelbine 60 mg/m2 D1, 8 and 15 Cycle of 28 days For a maximum of 12 cycles The dose of vinorelbine should be increased to 80 mg/m2 from the 2nd cycle If on D8 and D15, the administration conditions are not met, the administration is canceled and not delayed.

Trial Locations (16)

13385

Hôpital de la TIMONE, Marseille

31059

Hôpital des Enfants, Toulouse

33076

CHU de Bordeaux, Bordeaux

34000

CHRU Arnaud de Villeneuve, Montpellier

35203

CHU de Rennes - Hôpital Sud, Rennes

38043

CHU de Grenoble, Grenoble

49033

CHU d'Angers, Angers

51100

CHU de Reims, Reims

54500

CHU de Nancy, Nancy

59020

Centre Oscar Lambret, Lille

67098

Hôpital Hautepierre, Strasbourg

69373

Centre Léon Bérard, Lyon

75005

Institut Curie, Paris

76031

CHU de Rouen, Rouen

87042

CHU de Limoges, Limoges

94805

Institut Gustave Roussy, Villejuif

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Cancer Institute, France

OTHER_GOV

collaborator

Pierre Fabre Laboratories

INDUSTRY

lead

Centre Oscar Lambret

OTHER

NCT02197637 - Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma | Biotech Hunter | Biotech Hunter