NCT02187822 - Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

October 9, 2014

Primary Completion Date

February 20, 2018

Study Completion Date

March 31, 2018

Conditions

Brain MetastasesGeneralized Malignancy, PrimaryBrain Lesions

Interventions

DRUG

TPI 287

TPI 287 is an infusion given through veins. Dose escalation will begin at 14 mg/m\^2/dose. Dose expansion will begin at the maximum tolerated dose (MTD).

PROCEDURE

Fractionated Stereotactic Radiotherapy (FSRT)

The prescription dose will be 25 gray (Gy) in 5 daily fractions delivered to the planning target volume (PTV).

Trial Locations (1)

33612

H. Lee Moffitt Cancer Center and Research Institute, Tampa