A Pilot Study of CC-220 to Treat Systemic Lupus Erythematosus.

PHASE2CompletedINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

September 16, 2014

Primary Completion Date

September 25, 2018

Study Completion Date

September 25, 2018

Conditions
Systemic Lupus Erythematosus
Interventions
DRUG

CC-220

0.3 mg oral capsules once every other day with or without food

DRUG

CC-220

Subjects will receive 0.3 mg oral capsules every day with or without food

DRUG

CC-220

CC-220 oral capsules 0.6 mg and 0.3 mg on alternating days with or without food

DRUG

CC-220

CC-220 oral capsule 0.6 mg QD with or without food

DRUG

Placebo

Matching oral placebo daily

Trial Locations (35)

10016

NYU Langone Medical Center, New York

11030

Feinstein Institute For Medical Research, Manhasset

11042

Northwell Health / Division of Rheumatology, Lake Success

14642

Univ of Rochester Medical Center, Rochester

15261

UMPC Lupus Center of Excellence, Pittsburgh

16635

Altoona Center for Clinical Research, Duncansville

19104

University of Pennsylvania Health Systems, Philadelphia

23502

Virginia Clinical Research, Inc., Norfolk

28210

DJL Clinical Research, Charlotte

29406

Low Country Rheumatology PA, Charleston

30281

Arthritis Research and Treatment Center, Stockbridge

30303

Emory University School of Medicine, Atlanta

30342

Advanced Medical Research, Atlanta

33511

Vipul Joshi, MD, PA, dba Bay Area Arthritis and Osteoporosis, Brandon

35294

University of Alabama at Birmingham, Birmingham

43230

Ohio State University Medical Center, Columbus

43614

University of Toledo Medical Center, Toledo

44109

MetroHealth Medical Systems, Cleveland

60077

Northshore University Health System, Skokie

60611

Northwestern Medical Group; Department of Dermatology, Chicago

62794

Southern Illinois University School of Medicine, Springfield

70112

Tulane University Health Sciences Center, New Orleans

73104

Oklahoma Medical Research Foundation, Oklahoma City

77030

University of Texas Health Science Center at Houston, Houston

78731

Austin Regional Clinic, Austin

85253

Arizona Arthritis and Rheumatology Research, PLLC, Paradise Valley

85724

University of Arizona Clinical and Translational Science Research Center, Tucson

90045

Dermatology Research Associates, Los Angeles

90404

Clinical Science Institute, Santa Monica

90502

Los Angeles Biomedical Research Institute at Harbor - UCLA, Torrance

91786

Inland Rheumatology Clinical Trials, Upland

92037

UCSD Center for Innovative Therapy, La Jolla

94578

East Bay Rheumatology Medical Group Inc., San Leandro

98133

Seattle Arthritis Clinic, Seattle

10032-370

Columbia Presbyterian Medical Center, New York

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY