Respiratory Kinematics of Cough in Healthy Older Adults and Parkinson's Disease

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

August 31, 2015

Study Completion Date

August 31, 2015

Conditions
CoughParkinson's Disease
Interventions
DRUG

Capsaicin

For reflex cough testing, all participants will receive various concentrations of nebulized capsaicin. Delivery of multiple concentrations and doses of capsaicin allows for accurate assessment of both the strength (airflow measures) of reflex, as well as cough sensitivity.

OTHER

Voluntary cough test

Participants will be fitted with a facemask covering their mouth and nose, and instructed to cough into the facemask.

Trial Locations (2)

32611

Center for Movement Disorders and Neurorestoration, Gainesville

Dauer Hall, University of Florida, Gainesville

All Listed Sponsors
lead

University of Florida

OTHER

NCT02183519 - Respiratory Kinematics of Cough in Healthy Older Adults and Parkinson's Disease | Biotech Hunter | Biotech Hunter