Neurotoxin and Physical Therapy

PHASE4CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

December 31, 2014

Primary Completion Date

January 7, 2017

Study Completion Date

January 7, 2017

Conditions
Cervical Dystonia
Interventions
DRUG

Botox injection

Participants will receive a tailored dose of Botox to address their Cervical Dystonia symptoms

BEHAVIORAL

Physical Therapy

Participants will undergo physical therapy sessions with a physical therapist trained in movement disorders. Participants will be instructed to continue these exercises five times per week, and will be called weekly by the investigator to check progress.

PROCEDURE

Transcranial magnetic stimulation (TMS)

For these tests, participants will sit in a chair that looks like one found at the dentist's office. A nerve stimulator will be placed on the wrist of the right hand to stimulate the median and ulnar nerves. The intensity of the nerve stimulator will be gradually increased until the right thumb begins to twitch. A magnetic coil will be placed on the scalp on the left side of the head, overlying the brain's motor cortex, to stimulate the brain's output to the muscles in the opposite hand. This procedure will be repeated using the left wrist and the right side of the head.

Trial Locations (1)

32607

University of Florida, Gainesville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

American Academy of Neurology

OTHER

collaborator

National Ataxia Foundation

OTHER

collaborator

American Brain Foundation

OTHER

lead

University of Florida

OTHER

NCT02177617 - Neurotoxin and Physical Therapy | Biotech Hunter | Biotech Hunter