Safety and Efficacy of Two Different Doses of Ipratropium Bromide Versus ATROVENT® Inhalation Aerosol in Adults With Chronic Obstructive Pulmonary Disease

PHASE3CompletedINTERVENTIONAL

Enrollment

646

Participants

Timeline

Start Date

August 31, 1998

Primary Completion Date

October 31, 1999

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

DRUG

Low dose of Ipratropium bromide

One puff, 4 times daily by oral inhalation

DRUG

High dose of Ipratropium bromide

One puff, 4 times daily by oral inhalation

DRUG

Atrovent

Two puffs, 4 times daily by oral inhalation

DRUG

Placebo