Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus

PHASE2CompletedINTERVENTIONAL
Enrollment

104

Participants

Timeline

Start Date

June 30, 2014

Primary Completion Date

November 17, 2017

Study Completion Date

November 17, 2017

Conditions
DyspepsiaDiabetes Mellitus With Gastrointestinal Symptoms
Interventions
DRUG

Exendin 9-39

Exendin 9-39 will be administered intravenously (1,200 pmol/kg bolus followed by infusion at 300 pmol/kg/min).

DRUG

Microlipid

Lipid infusion {66.7 mL Microlipid (0.5 gm/mL diluted in water to 222 ml).

DRUG

Placebo

Normal saline infusion will be prepared to match the appearance of Exendin 9-39

Trial Locations (1)

55905

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Mayo Clinic

OTHER