Does Guanfacine Attenuate Stress-Induced Drinking?

PHASE2CompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

June 30, 2014

Primary Completion Date

March 31, 2020

Study Completion Date

March 31, 2020

Conditions
Alcohol Drinking
Interventions
DRUG

Guanfacine 3mg/day

3 mg/day Guanfacine with 3-week lead-in period. Maintained at steady state throughout lab sessions. After lab sessions, given taper supply of medication. Follow up 2 weeks after completion of taper.

DRUG

Guanfacine 1.5mg/day

1.5 mg/day Guanfacine with 3-week lead-in period. Maintained at steady state throughout lab sessions. After lab sessions, given taper supply of medication. Follow up 2 weeks after completion of taper.

DRUG

Placebo

Trial Locations (1)

06519

Yale Center for Clinical Investigations, Yale University, New Haven

All Listed Sponsors
collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

Yale University

OTHER

NCT02164422 - Does Guanfacine Attenuate Stress-Induced Drinking? | Biotech Hunter | Biotech Hunter