Translation Evaluation of Aging, Inflammation and HIV in Lung Function (TEAL)

CompletedOBSERVATIONAL
Enrollment

323

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

March 2, 2020

Study Completion Date

March 2, 2020

Conditions
HIVCOPDPulmonary DiseaseAging
Interventions
PROCEDURE

PFT

Lung function endpoints of FVC, FEV1, FEV1/FVC, and FEF25-75% will be measured with the flow-volume loop recorder on a NDD EasyOne Pro system before and after bronchodilator administration.

PROCEDURE

lab work

The blood will be processed for serum, plasma, and PBMCS, and a portion stored to be used for future use. A hemoglobin and Carboxyhemoglobin will be done in order to calculate the DLCO.

PROCEDURE

6MWT

The six-minute walk tests are performed in a 100-foot segment of straight hallway marked at 1-foot intervals.

OTHER

questionnaires

TEAL, MMRC and ST. George's Questionnaire will be administered. They are paper questionnaires that inquire about respiratory symptoms, quality of life, smoking history and other health issues

Trial Locations (1)

15213

University of Pittsburgh, Pittsburgh

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Pittsburgh

OTHER

NCT02154880 - Translation Evaluation of Aging, Inflammation and HIV in Lung Function (TEAL) | Biotech Hunter | Biotech Hunter