323
Participants
Start Date
February 28, 2014
Primary Completion Date
March 2, 2020
Study Completion Date
March 2, 2020
PFT
Lung function endpoints of FVC, FEV1, FEV1/FVC, and FEF25-75% will be measured with the flow-volume loop recorder on a NDD EasyOne Pro system before and after bronchodilator administration.
lab work
The blood will be processed for serum, plasma, and PBMCS, and a portion stored to be used for future use. A hemoglobin and Carboxyhemoglobin will be done in order to calculate the DLCO.
6MWT
The six-minute walk tests are performed in a 100-foot segment of straight hallway marked at 1-foot intervals.
questionnaires
TEAL, MMRC and ST. George's Questionnaire will be administered. They are paper questionnaires that inquire about respiratory symptoms, quality of life, smoking history and other health issues
University of Pittsburgh, Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI)
NIH
University of Pittsburgh
OTHER