Endometrial Injury and in Vitro Fertilization Outcomes

NACompletedINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

August 31, 2014

Primary Completion Date

June 30, 2017

Study Completion Date

December 31, 2018

Conditions
Infertility
Interventions
PROCEDURE

Endometrial Scratch

After cleansing the cervix with Betadine, the procedure will be performed using a 3mm endometrial sampling curette, with three passes made of the endometrium along the length of the fundus. Patients will be given the option to take ibuprofen 600mg one hour prior to the scheduled procedure. The first endometrial scratch procedure or sham procedure will be performed up to two weeks prior to expected menses, and the second endometrial scratch or sham procedure will be performed cycle day 5-11 of the stimulation cycle.

PROCEDURE

Sham procedure

For the sham procedure, after cleansing the cervix with betadine, the endometrial sampling curette will be placed 2-3cm into the cervix without entering the uterine cavity

Trial Locations (1)

60611

Northwestern Medical Faculty Foundation, Division of Reproductive Endocrinology and Infertility, Chicago

All Listed Sponsors
collaborator

Northwestern Memorial Hospital

OTHER

lead

Northwestern University

OTHER

NCT02153814 - Endometrial Injury and in Vitro Fertilization Outcomes | Biotech Hunter | Biotech Hunter