Immunogenicity of H5N1 Vaccine Following H5N2

PHASE2CompletedINTERVENTIONAL
Enrollment

43

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

September 30, 2014

Study Completion Date

September 30, 2014

Conditions
Influenza Vaccine
Interventions
BIOLOGICAL

A(H5N1) inactivated influenza vaccine (IIV)

Prepared from the NIBRG-23 vaccine virus strain. One vaccine dose (0.5 ml) contained 15 mg of influenza A(H5N1) virus hemagglutinin (HA), adjuvanted with aluminum hydroxide. Two doses were administered intramuscularly 28 days apart.

BIOLOGICAL

A(H5N2) live attenuated influenza vaccine (LAIV)

Two doses of A(H5N2) live attenuated influenza vaccine (LAIV) administered 28 days apart, approximately 1.5 years prior to receiving A(H5N1) IIV

Trial Locations (1)

Unknown

Research Institute of Influenza, Saint Petersburg

All Listed Sponsors
collaborator

Institute of Experimental Medicine, Russia

OTHER

collaborator

Research Institute of Influenza, Russia

OTHER

lead

PATH

OTHER

NCT02153671 - Immunogenicity of H5N1 Vaccine Following H5N2 | Biotech Hunter | Biotech Hunter