NCT02153229View on ClinicalTrials.gov

Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

June 2, 2014

Primary Completion Date

November 11, 2024

Study Completion Date

December 31, 2025

Conditions
Epitheliod Malignant Pleural Mesothelioma
Interventions
RADIATION

Photodynamic Therapy

PROCEDURE

Radical Pleurectomy

RADIATION

Chemotherapy

DRUG

Photofrin 2.0 mg/kg

If randomized to the RP with PDT arm, subject will receive Photofrin 2.0 mg/kg as an intravenous infusion 24 hours (range 18-30 hours) prior to intra-operative light delivery (PDT) during radical pleurectectomy

Trial Locations (2)

14263

Roswell Park Cancer Institute, Buffalo

19104

University of Pennsylvania, Philadelphia

All Listed Sponsors
lead

Abramson Cancer Center at Penn Medicine

OTHER