Implantation Enhancement by Elective Cryopreservation of All Viable Embryos

NACompletedINTERVENTIONAL
Enrollment

212

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

February 28, 2017

Study Completion Date

February 28, 2017

Conditions
InfertilityOHSS
Interventions
PROCEDURE

Vitrification with subsequent-cycle embryo thawing/transfer

"The vitrification process will be performed under the same conditions of all other vitrification procedures usually performed in our centre. In summary, vitrification will be accomplished using closed high security straws (CryoBioSystem®) in combination with dimethylsulfoxide, ethylene glycol and sucrose as cryoprotectants (Irvine ScientificR Freeze Kit®).~In the meantime, patients will wait for a subsequent cycle before starting exogenous hormone therapy for endometrial preparation."

PROCEDURE

Intensified luteal phase support for fresh embryo transfer

A single administration of 1500 IU of exogenous hCG (Pregnyl®) 1 hour after oocyte retrieval followed by daily vaginally-administered progesterone 200 mg tid (Utrogestan®) and oestradiol valerate 2 mg bid (Progynova®).

DRUG

Pregnyl®

1500 IU

DRUG

Utrogestan®

200 mg tid

DRUG

Progynova®

2 mg bid

DEVICE

CryoBioSystem®

CryoBioSystem® in combination with dimethylsulfoxide, ethylene glycol and sucrose as cryoprotectants (Irvine ScientificR Freeze Kit®) closed in high security straws

Trial Locations (1)

1600-548

Universitair Ziekenhuis Brussel, Brussels

All Listed Sponsors
lead

Universitair Ziekenhuis Brussel

OTHER

NCT02148393 - Implantation Enhancement by Elective Cryopreservation of All Viable Embryos | Biotech Hunter | Biotech Hunter