European Long-acting Antipsychotics in Schizophrenia Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

536

Participants

Timeline

Start Date

February 28, 2015

Primary Completion Date

August 26, 2020

Study Completion Date

August 26, 2020

Conditions
Schizophrenia
Interventions
DRUG

Aripiprazole

Administration in once-a-day schedule without regard to meals.

DRUG

Aripiprazole depot

Abilify Maintena is an intramuscular (IM) depot formulation of oral aripiprazole. It provides the efficacy and safety profile of oral aripiprazole in a once-monthly injection.

DRUG

Paliperidone

Administration once a day orally standardised in relation to food intake.

DRUG

Paliperidone palmitate

In selected patients with schizophrenia and previous responsiveness to oral paliperidone or risperidone, Xeplion may be used without prior stabilization with oral treatment if psychotic symptoms are mild to moderate and a long-acting injectable is needed.

Trial Locations (49)

1030

Psychosoziale Dienste, Vienna

1113

University Hospital of Neurology and Psychiatry 'St. Naum' 1, Sofia

2060

ZNA, department of Psychiatry, locatie Stuivenberg, Antwerp

2570

Psychiatrisch Ziekenhuis Duffel, Antwerp

2600

Center for Neuropsychiatric Research, Glostrup Municipality

5021

Helse Bergen HF Haukeland University Hospital, Division of Psychiatry, Bergen

7441

St Olavs Hospital avd Østmarka / INM NTNU, Trondheim

10126

Università degli Studi di Torino. Dipartimento di Neuroscienze, Turin

33006

Facultad de Medicina Center, Oviedo

39011

Hospital Universitario Marqués de Valdecilla, Servicio de Psiquiatría, Santander

40629

Klinik und Poliklinik für Psychiatrie und Psychotherapie der Heinrich-Heine-Universität, Düsseldorf

52621

The Chaim Sheba Medical Center, Tel Litwinsky

80138

Department of Psychiatry, University of Naples SUN, Naples

80336

Department of Psychiatry and Psychotherapy, München

81675

Technische Universität München (TUM, München

A-6020

Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck

500 05

Psychiatrická klinika LF UK, Hradec Králové

Unknown

Dr. Ustohal, Brno

Dr. Mohr, Prague

National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens

Dr. Csekey, Balassagyarmat

Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest

Abravanel Mental Health Center, Bat Yam

Be'er-Ness Mental Health Center, Be’er Ya‘aqov

The Jerusalem Mental Health Center, Jerusalem

Lev-Hasharon Medical Center for Mental Health, Pardesiyya

Geha Medical Health Center, Petah Tikva

"Servizio Psichiatrico Universitario di Diagnosi e Cura. Presidio Ospedaliero San Salvatore Università degli Studi dell'Aquila.", L’Aquila

University Medical Center, Utrecht

Stavanger University Hospital, Stavanger

Spitalul Clinic Judetean de Urgenta Arad - Clinica de Psihiatrie, Arad

"Spitalul Clinic de Psihiatrie Prof. Dr. Alexandru Obregia", Bucharest

"Spitalul Clinic de Psihiatrie Prof. Dr. Alexandru Obregia", Bucharest

Spitalul de Psihiatrie si pentru Masuri de Siguranta, Sapoca, Buzau, Buzău

Spitalul Clinic de Neuropsihiatrie Craiova, Craiova

Sitalul Clinic Judetean Mures, Targu Mureş

Child and Adolescent Psychiatry Department. Hospital General Universitario Gregorio Marañón. Servicio Madrileño de Salud, Madrid

Greater Manchester West Mental Health NHS Foundation Trust, Manchester

Edmund Ward, St Martins Hospital Littlebourne Road Canterbury, Kent

Imperial College, Centre for Mental Health, Faculty of Medicine,, London

Tees, Ask and Wearvalleys, Middlesbrough

Northumberland, Newcastle

Oxford Health NHS Foundation Trust, Oxford

Surrey and Borders Partnership NHS Foundation Trust, Surrey

06112

Klinik für Psychiatrie, Psychotherapie und Psychosomatik der Martin-Luther-Universität, Halle

02-957

Instytut psychiatrii i neurologii, Warsaw

20-439

II Klinika Psychiatrii Uniwersytet Medyczny w Lublinie, Lublin

08036

Hospital Clínic de Barcelona. Unidad de Esquizofrenia, Barcelona

W38NJ

West London Mental Health Trust. East Recovery Team, London

All Listed Sponsors
lead

UMC Utrecht

OTHER

NCT02146547 - European Long-acting Antipsychotics in Schizophrenia Trial | Biotech Hunter | Biotech Hunter