Airway and Pulmonary Vascular Endothelial Function in Healthy Smokers: Effect of Inhaled Glucocorticosteroid Treatment

NACompletedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

April 30, 2013

Primary Completion Date

June 30, 2015

Study Completion Date

December 31, 2015

Conditions
Smoking
Interventions
PROCEDURE

echocardiogram plus albuterol

participants will performed echocardiogram before and 15 minutes after inhaled albuterol

PROCEDURE

airway blood flow plus albuterol

participants will performed echocardiogram before and 15 minutes after inhaled albuterol

DRUG

Fluticasone propionate

participant will be received a 4-week course of inhaled fluticasone (220 μg fluticasone twice a day administered as a MDI using a spacer)

DRUG

placebo

participant will be received a 4-week course of identically appearing placebo (2 puffs twice a day via spacer).

Trial Locations (1)

33136

University of Miami School of Medicine, Miami

All Listed Sponsors
lead

University of Miami

OTHER

NCT02141633 - Airway and Pulmonary Vascular Endothelial Function in Healthy Smokers: Effect of Inhaled Glucocorticosteroid Treatment | Biotech Hunter | Biotech Hunter