Physical Exercise in OCD: Treatment Efficacy, Additive Benefits to CBT, and Cognitive Correlates of Change

NACompletedINTERVENTIONAL
Enrollment

125

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

October 31, 2017

Study Completion Date

August 30, 2019

Conditions
Obsessive-Compulsive DisorderCognition Disorders
Interventions
BEHAVIORAL

Exercise

12 weeks of structured aerobic exercise, 3 times a week, following a two-stage graduated regimen: 1) Initial stage (weeks 1-4): 40-60% intensity, 15-30 min duration (+ 5 min warm-up/cool-down), and 2) Improvement stage (weeks 5-12): 60-80% intensity, 30-45 min duration. Adherence measures include self-reported exercise session logs and weekly phone checks by research assistants.

BEHAVIORAL

Cognitive Behavioural Therapy (CBT)

CBT will be delivered in group format, 2 hours per week, for 12 consecutive weeks with 8-10 participants per group and will be conducted according to a session-by-session treatment manual that incorporates Exposure and Response Prevention (ERP) in the early phases of treatment and then increases emphasis on cognitive approaches for obsessions and compulsions outlined in step-by-step strategies.

Trial Locations (3)

L8N 4A6

St. Joseph's Healthcare Hamilton at McMaster University, Hamilton

M4N 3M5

Sunnybrook Health Sciences Centre, Toronto

M5T 1R8

Centre for Addiction and Mental Health, Toronto

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

Centre for Addiction and Mental Health

OTHER

collaborator

McMaster University

OTHER

collaborator

Toronto Metropolitan University

OTHER

lead

Sunnybrook Health Sciences Centre

OTHER

NCT02136953 - Physical Exercise in OCD: Treatment Efficacy, Additive Benefits to CBT, and Cognitive Correlates of Change | Biotech Hunter | Biotech Hunter