20
Participants
Start Date
June 30, 2014
Primary Completion Date
September 30, 2014
Study Completion Date
September 30, 2014
Bed rest
8 days of full bed rest
OGTT
Oral glucose tolerance test with 75 g of glucose before and after bed rest
IVGTT
Intravenous glucose tolerance test mimicking the glucose profile from the corresponding OGTT
Cognitive testing
Daily testing of memory and concentration using standardized tests
Muscle and fat biopsies
Biopsies will be obtained before and after bed rest
Dual-energy X-ray Absorptiometry (DXA) scan
DXA scan to evaluate fat and muscle distribution before and after bed rest
MRI
Functional MRI to evaluate cognitive function and abdominal MRI to evaluate visceral fat before and after bed rest
Rigshospitalet, Copenhagen
Rigshospitalet, Denmark
OTHER