NCT02131545 - Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

June 30, 2014

Primary Completion Date

July 31, 2016

Study Completion Date

July 31, 2016

Conditions

DementiaDelirium

Interventions

DRUG

Quetiapine 25 mg gel applied topically

Quetiapine 25 mg gel applied topically; 9 serum quetiapine levels drawn over the course of 8 hours

DRUG

Quetiapine 25 mg tablet by mouth

Quetiapine 25 mg tablet administered by mouth; 9 serum quetiapine levels drawn over the course of 8 hours

DRUG

Quetiapine 25 mg rectal suppository

Quetiapine 25 mg suppository administered rectally; 9 serum quetiapine levels drawn over the course of 8 hours

DRUG

Quetiapine 25 mg gel applied topically

Quetiapine 75 mg gel applied topically every 4 hours for 24 hours; 6 serum quetiapine levels drawn over the course of 24 hours

Trial Locations (1)

Mayo Clinic in Rochester, Rochester