A Dose Escalation Study of PF-06650808 in Patients With Advanced Solid Tumors

PHASE1TerminatedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 30, 2014

Primary Completion Date

July 31, 2017

Study Completion Date

July 31, 2017

Conditions
NeoplasmsBreast Cancer
Interventions
DRUG

PF-06650808

Dose Escalation Phase \[Part 1\] - PF-06650808 will be administered at doses starting at 0.2 mg/kg. Increases in dose will continue until MTD is determined.

DRUG

PF-06650808

Dose Expansion Phase \[Part 2\] - Patients will be treated at the MTD or Recommended Phase 2 dose selected in Part 1.

Trial Locations (11)

43210

The Ohio State University James Cancer Hospital, Columbus

The OSU Investigational Drug Services, Columbus

43212

The OSU Stephanie Spielman Comprehensive Breast Center, Columbus

43221

The Ohio State University Martha Morehouse Medical Plaza, Columbus

78229

South Texas Accelerated Research Therapeutics, LLC (START), San Antonio

90095

Ronald Reagan UCLA Medical Center, Drug Information Center, Los Angeles

Ronald Reagan UCLA Medical Center, Los Angeles

UCLA Hematology/Oncology, Los Angeles

Westwood Bowyer Clinic, Los Angeles

90404

Santa Monica - UCLA Medical Center & Orthopaedic Hospital, Santa Monica

UCLA Hematology/Oncology - Santa Monica, Santa Monica

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY