NCT02129101 - Azacitidine and Sonidegib or Decitabine in Treating Patients With Myeloid Malignancies | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

December 31, 2016

Study Completion Date

October 25, 2019

Conditions

Chronic Myelomonocytic Leukemiade Novo Myelodysplastic SyndromeEssential ThrombocythemiaMyelodysplastic SyndromeMyelodysplastic/Myeloproliferative NeoplasmPolycythemia VeraPreviously Treated Myelodysplastic SyndromePrimary MyelofibrosisRecurrent Adult Acute Myeloid LeukemiaRecurrent Childhood Acute Myeloid LeukemiaUntreated Adult Acute Myeloid Leukemia

Interventions

DRUG

Azacitidine

Given SC or IV

DRUG

Decitabine

Given IV

OTHER

Laboratory Biomarker Analysis

Correlative studies

OTHER

Quality-of-Life Assessment

Ancillary studies

DRUG

Sonidegib

Given PO

Trial Locations (1)

55905

Mayo Clinic, Rochester