Non-Invasive Cardiac Output Measurement for CRT Optimization

"1. Baseline CO measurement by NICaS~2. AV delay optimization:~ 1. AV delay will be changed (increase and decrease) by 30 ms steps , and for each new AV value, the CO will be real-time measured by NICaS~ 2. The AV delay yielding the maximal CO, will be considered the optimal AV delay~ 3. The device will be programmed using the optimal AV delay~3. VV delay optimization:~ 1. After Step 2, the baseline VV delay will be changed (increase and decrease; meaning that we will be pacing alternatively the LV before the RV, then the RV before the LV), by 30 ms steps, and for each new VV value, the CO will be real-time measured by NICaS~ 2. The VV delay yielding the maximal CO, will be considered the optimal VV delay~ 3. The device will be programmed using the optimal VV delay"