Alteration of Temporal Organization of EEG Microstate Sequences During Propofol-induced Loss of Consciousness

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

April 30, 2015

Study Completion Date

April 30, 2015

Conditions
Loss of Consciousness
Interventions
DEVICE

Target Controlled Infusion system (Orchestra Base Primea, Fresenius, France)

Intravenous induction with propofol using the pharmacokinetic model by Schnider et al. The initial cerebral concentration will be 0.5 µg ml-1, which will be increased stepwise by 1.0 µg ml-1 until 2.5 µg ml-1, and then by 0.5 µg ml-1 until loss of consciousness

Trial Locations (1)

1206

University Hospitals of Geneva, Geneva

All Listed Sponsors
collaborator

University of Geneva, Switzerland

OTHER

collaborator

Ecole Polytechnique Fédérale de Lausanne

OTHER

lead

Julien Maillard

OTHER

NCT02125214 - Alteration of Temporal Organization of EEG Microstate Sequences During Propofol-induced Loss of Consciousness | Biotech Hunter | Biotech Hunter