BI 836845 in Estrogen Receptor Positive Metastatic Breast Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

164

Participants

Timeline

Start Date

May 15, 2014

Primary Completion Date

November 25, 2016

Study Completion Date

December 14, 2021

Conditions
Neoplasms
Interventions
DRUG

Everolimus

10mg dose

DRUG

Exemestane

Fixed dose at 25mg

DRUG

BI 836845

1000 mg, recommended dose per Phase Ib part. Human monoclonal antibody. Dose escalation in Phase Ib. 2 dose levels (high or low) depending on the dose cohort explored

Trial Locations (38)

112

Taipei Veterans General Hospital, Taipei

1090

Brussels - UNIV UZ Brussel, Brussels

1160

Wilhelminenspital, Vienna

1200

Brussels - UNIV Saint-Luc, Brussels

2650

Edegem - UNIV UZ Antwerpen, Edegem

3000

UZ Leuven, Leuven

4000

Centre Hospitalier Universitaire de Liège, Liège

Liège - HOSP St-Joseph, Liège

5000

CHU UCL Namur - Site De Sainte-Elisabeth, Namur

6000

Charleroi - HOSP Grand Hôpital de Charleroi, Charleroi

8036

Medical University of Graz State Hospital - University Hospital Graz, Graz

8807

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City

10002

National Taiwan University Hospital, Taipei

10408

National Cancer Center, Goyang

13009

INS Paoli-Calmettes, Marseille

22190

Ctr Cario, Plerin Sur Mer

25030

HOP Jean Minjoz, Besançon

25198

Hospital Arnau de Vilanova, Lleida

28033

MD Anderson Cancer Center Madrid, Madrid

28034

Hospital Ramón y Cajal, Madrid

28040

Hospital Clínico San Carlos, Madrid

28041

Hospital Universitario 12 de Octubre, Madrid

40705

Taichung Veterans General Hospital, Taichung

41013

Hospital Virgen del Rocío, Seville

44202

CTR Catherine de Sienne, Nantes

46010

Hospital Clínico de Valencia, Valencia

75015

HOP Européen G. Pompidou, Paris

75248

INS Curie, Paris

D04 T6F4

St. Vincent's University Hospital, Dublin

6229 HX

Maastricht University, Maastricht

110-744

Seoul National University Hospital, Seoul

138-736

Asan Medical Center, Seoul

08035

Hospital Vall d'Hebron, Barcelona

08036

Hospital Clínic de Barcelona, Barcelona

171 76

Centrummottagningen, Stockholm

DD1 9SY

Ninewells Hospital & Medical School, Dundee

EC1M 6BQ

St Bartholomew's Hospital, London

NE7 7DN

Freeman Hospital, Newcastle upon Tyne

Sponsors
All Listed Sponsors
lead

Boehringer Ingelheim

INDUSTRY