A Study Of PF-06664178 In Patients With Advanced Solid Tumors

PHASE1TerminatedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

August 31, 2014

Primary Completion Date

June 30, 2016

Study Completion Date

June 30, 2016

Conditions
Neoplasms
Interventions
DRUG

PF-06664178

Part 1 - PF-06664178 will be administered intravenously every 21 days in cohorts of 2 or more patients starting at a dose of 0.15 mg/kg. Increases in dose will continue until MTD is determined.

DRUG

PF-06664178

Part 2 - patients with select tumor types (Non Small Cell Lung Cancer ovarian cancer, and breast cancer ) will be treated at the MTD selected in Part 1.

Trial Locations (10)

80045

Anschutz Cancer Pavilion, Aurora

University of Colorado Denver CTO (CTRC), Aurora

University of Colorado Hospital, Aurora

90033

Keck Hospital of USC, Los Angeles

LAC&USC Medical Center, Los Angeles

USC/Norris Comprehensive Cancer Center / Investigational Drug Services, Los Angeles

USC/Norris Comprehensive Cancer Center, Los Angeles

98104

Swedish Medical Center, Seattle

98109

Seattle Cancer Care Alliance, Seattle

98195

University of Washington Medical Center, Seattle

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY