Border Zone Stereotactic Radiosurgery With Bevacizumab in Patients With Glioblastoma Multiforme

PHASE2CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

March 31, 2018

Study Completion Date

March 31, 2018

Conditions
Glioblastoma MultiformeGlioblastoma - Category
Interventions
DRUG

Bevacizumab

Patients will receive bevacizumab (10 mg/kg) one day before and then at day 14 followed by10 mg/kg/day every 14 days until progression.

PROCEDURE

Magnetic Resonance Spectroscopy (MRS)

Subjects will have MRS prior to BZ-SRS.

PROCEDURE

Border Zone Stereotactic Radiosurgery (BZ-SRS)

The 'border zone' of the tumor will be targeted by SRS in a single session.

Trial Locations (1)

15213

University of Pittsburgh, Pittsburgh

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

Ajay Niranjan

OTHER

NCT02120287 - Border Zone Stereotactic Radiosurgery With Bevacizumab in Patients With Glioblastoma Multiforme | Biotech Hunter | Biotech Hunter