Transforming Research and Clinical Knowledge in Traumatic Brain Injury

CompletedOBSERVATIONAL
Enrollment

2,996

Participants

Timeline

Start Date

March 2, 2014

Primary Completion Date

June 22, 2019

Study Completion Date

August 31, 2020

Conditions
Traumatic Brain Injury
Interventions
BEHAVIORAL

In-Person Outcome Assessment

NIH Flexible Outcome Assessment Battery Framework Measures In-Person at 2 Weeks, 6 Months, and 12 Months, and by Phone at 3 Months.

BEHAVIORAL

Phone Outcome Assessment

NIH Flexible Outcome Assessment Battery Framework Measures by Phone at 2 Weeks, 3 Months, 6 Months, and 12 Months.

PROCEDURE

3T Magnetic Resonance Imaging (MRI)

3T Research MRI at 2 weeks and 6 months.

PROCEDURE

Blood Draw for Plasma, DNA, Serum, RNA

Blood Draw for Plasma, DNA, Serum, RNA at baseline, in hospital (if applicable), 2 weeks, and 6 months (DNA at baseline only).

Trial Locations (23)

15213

University of Pittsburgh Medical Center, Pittsburgh

19104

University of Pennsylvania/Penn Presbyterian Medical Center, Philadelphia

21201

University of Maryland, Baltimore

23298

Virginia Commonwealth University, Richmond

30303

Emory University, Atlanta

33136

University of Miami, Miami

45267

University of Cincinnati, Cincinnati

46202

Indiana University, Indianapolis

53226

Medical College of Wisconsin, Milwaukee

55415

University of Minnesota/Hennepin County Medical Center, Minneapolis

75390

University of Texas Southwestern, Dallas

77030

Baylor College of Medicine, Houston

TIRR Memorial Hermann, Houston

University of Texas Health Science Center at Houston, Houston

78701

Dell Seton Medical Center, Austin

78712

University of Texas at Austin, Austin

80113

University of Colorado/Craig Hospital, Englewood

80204

Denver Health and Hospitals Authority, Denver

84132

University of Utah, Salt Lake City

94110

University of California, San Francisco, San Francisco

98104

University of Washington, Seattle

02114

Massachusetts General Hospital, Boston

02129

Spaulding Rehabilitation Hospital, Charlestown

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

collaborator

Department of Health and Human Services

FED

lead

University of California, San Francisco

OTHER

NCT02119182 - Transforming Research and Clinical Knowledge in Traumatic Brain Injury | Biotech Hunter | Biotech Hunter