The Effect of Low Furanocoumarin Grapefruit Hybrid Juice Consumption on Midazolam Pharmacokinetics

PHASE4CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

May 31, 2015

Study Completion Date

May 31, 2015

Conditions
Pharmacokinetics
Interventions
OTHER

Low furanocoumarin hybrid grapefruit juice

3 consecutive daily doses of 200ml low furanocoumarin grapefruit juice plus midazolam 5mg orally on the third day.

OTHER

Regular grapefruit juice

3 consecutive daily doses of 200ml regular grapefruit juice plus midazolam 5mg orally on the third day.

OTHER

Water (control)

3 consecutive daily doses of 200ml water plus midazolam 5mg orally on the third day.

Trial Locations (1)

32611

Clinical Research Center, Gainesville

All Listed Sponsors
lead

University of Florida

OTHER

NCT02117869 - The Effect of Low Furanocoumarin Grapefruit Hybrid Juice Consumption on Midazolam Pharmacokinetics | Biotech Hunter | Biotech Hunter