74
Participants
Start Date
April 30, 2014
Primary Completion Date
December 31, 2026
Study Completion Date
January 31, 2027
Antioxidant cocktail
Flow-Mediated Dilation will be determined at baseline and 2 hours following acute antioxidant treatment
Biopsy
Under sterile conditions, a small incision (¼ - ½ inch) by the study doctor will be made and the piece of fat will be taken out. Fat tissue was chosen for this study because it is a big source of small blood vessels which we are studying
Placebo
Flow-Mediated Dilation will be determined at baseline and 2 hours following acute antioxidant treatment
NMD; 0.4mg sub-lingual nitroglycerin spray
Nitroglycerin mediated dilation will be measured immediately following an administered 0.4mg dose of nitroglycerin spray, sub-lingual.
Georgia Prevention Institute , Georgia Regents University, Augusta
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Augusta University
OTHER