Propranolol and Botulinum Toxin for Essential Vocal Tremor

PHASE4CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

October 31, 2014

Study Completion Date

November 30, 2014

Conditions
Essential Vocal TremorEssential Voice TremorEssential TremorVoice TremorVocal Tremor
Interventions
DRUG

Propranolol

After a discussion of the risks and benefits of propranolol therapy, the patient will then be given a prescription by the principal investigator for propranolol. This prescription will consist of a starting dose of generic immediate-release at 10 mg three times daily (30 mg each day) with an increase in dose in 5-7 days if there is no effect (60 mg each day) and if the patient had demonstrated no side effects. Dose may be increased to 240 mg each day depending on patient improvement and side effect profile.

PROCEDURE

Botulinum Toxin

At the second evaluation, patient will receive botulinum toxin injections. The risks and benefits of botulinum toxin therapy will be explained to the patient, and bilateral injections will take place.

Trial Locations (1)

30308

Emory Voice Center, Atlanta

All Listed Sponsors
lead

Emory University

OTHER

NCT02111369 - Propranolol and Botulinum Toxin for Essential Vocal Tremor | Biotech Hunter | Biotech Hunter