Quantitative Detection of Circulating Donor-Specific DNA in Organ Transplant Recipients (DTRT-Multi-Center Study)

CompletedOBSERVATIONAL
Enrollment

540

Participants

Timeline

Start Date

March 1, 2014

Primary Completion Date

March 30, 2020

Study Completion Date

March 30, 2020

Conditions
Cardiovascular DiseaseAcute Rejection of Cardiac TransplantCardiac Transplant RejectionHeart Transplant Failure and Rejection
Interventions
DIAGNOSTIC_TEST

Blood Draw of up to 10 ml

In a laboratory setting, the blood will be spun for plasma and buffy coat, DNA will be extracted for processing using the diagnostic test. The results of the test are not provided back to the clinical setting.

Trial Locations (8)

10032

Columbia University, New York

27711

Duke University, Durham

30322

Emory University, Atlanta

37212

Vanderbilt University, Nashville

53226

Children's Hospital of Wisconsin, Milwaukee

Froedtert Hospital, Milwaukee

60611

Ann & Robert H. Lurie Children's Hospital Chicago, Chicago

72202

Arkansas Children's Hosoptial Research Institute, Little Rock

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

Columbia University

OTHER

collaborator

Duke University

OTHER

collaborator

Arkansas Children's Hospital Research Institute

OTHER

collaborator

Emory University

OTHER

collaborator

Children's Healthcare of Atlanta

OTHER

collaborator

Vanderbilt University

OTHER

collaborator

TAI Diagnostics, Inc.

INDUSTRY

collaborator

Ann & Robert H Lurie Children's Hospital of Chicago

OTHER

collaborator

Children's Hospital and Health System Foundation, Wisconsin

OTHER

collaborator

University of California, Los Angeles

OTHER

collaborator

Children's Hospital Medical Center, Cincinnati

OTHER

collaborator

Phoenix Children's Hospital

OTHER

collaborator

The Cleveland Clinic

OTHER

lead

Medical College of Wisconsin

OTHER