Effectiveness Study of Circumferential vs. Segmental Ablation in Paroxysmal Atrial Fibrillation

NACompletedINTERVENTIONAL
Enrollment

97

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

December 31, 2021

Study Completion Date

December 31, 2021

Conditions
Paroxysmal Atrial FibrillationAtrial Arrhythmia
Interventions
PROCEDURE

Circumferential Pulmonary Vein Ablation

Contiguous ablation lesions will be performed to encircle the two left and right pulmonary veins (PVs) of the left atrium, guided by 3D electroanatomic mapping. After completion of the circumferential ablation, PV isolation will be confirmed by the mapping catheter, and further focal ablation performed as required until electrical PV isolation is confirmed.

PROCEDURE

Segmental Pulmonary Vein Isolation

Electrical potentials recorded in the pulmonary vein (PV) ostium using a circular mapping catheter, representing electrical connections between the left atrium and PVs will be ablated at or just proximal to the PV ostium in the PV antrum. Ablation will be performed segmentally at multiple sites guided by the mapping catheter until mapping demonstrates elimination of all PV potentials.

Trial Locations (1)

92093

UCSD Sulpizio Cardiovascular Center, La Jolla

All Listed Sponsors
lead

University of California, San Diego

OTHER

NCT02106663 - Effectiveness Study of Circumferential vs. Segmental Ablation in Paroxysmal Atrial Fibrillation | Biotech Hunter | Biotech Hunter