Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)

PHASE4CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

April 30, 2014

Primary Completion Date

April 13, 2017

Study Completion Date

April 13, 2017

Conditions
Labor PainComplications; Cesarean SectionPregnancy
Interventions
DRUG

Epidural anesthesia

"An epidural involves injecting pain-blocking medication into a space between the vertebrae and the spinal fluid; it usually takes about 15 minutes to work.~Epidurals will be placed in a sterile fashion using a 17g Tuohy needle to locate the epidural space via loss-of-resistance to saline at the lumbar vertebral level. 3 ml of 1.5% lidocaine with 5ug/ml of epinephrine will then be used for test dose to exclude intrathecal or intravenous placement of the catheter. Epidural solution composed of 5ml of 0.2% ropivacaine and another 5 ml of 0.2% ropivacaine will then be administered."

DRUG

Combined spinal and epidural anesthesia

"A spinal is an injection directly into the spinal fluid; it is given in addition to the epidural technique and takes effect in five minutes.~The epidural space will be located with a 17g Tuohy needle and dural puncture performed with 25g Pencan needle via needle-through-needle technique. Spinal injection of 2ml 0.2% ropivacaine will then be performed and spinal needle removed. An epidural catheter will then be placed and test dose performed with 3 ml of 1.5% lidocaine with 5ug/ml of epinephrine. Maintenance dose will be via an epidural pump using 0.2% ropivacaine at a rate of 12 ml/hr."

Trial Locations (1)

77026

Lyndon B. Johnson Hospital, Houston

All Listed Sponsors
lead

The University of Texas Health Science Center, Houston

OTHER

NCT02105558 - Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC) | Biotech Hunter | Biotech Hunter