NCT02097329View on ClinicalTrials.gov

Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And Food

PHASE1CompletedINTERVENTIONAL

Enrollment

27

Participants

Timeline

Start Date

April 30, 2014

Primary Completion Date

June 30, 2014

Study Completion Date

June 30, 2014

Conditions

Healthy

Interventions

DRUG

palbociclib commercial free base

125 mg oral capsule single dose

DRUG

famotidine

20 mg oral tablet 10 hours before and 2 hours after palbociclib

DRUG

rabeprazole

2 x 20 mg oral tablets daily for 6 days then on 7th day, 4 hours after palbociclib

DRUG

palbociclib commercial free base

125 mg oral capsule single dose

DRUG

antacid

30 mL orally once (2h before palbociclib)

DRUG

antacid

30 mL orally once (2h after palbociclib)

Trial Locations (1)

06511

Pfizer Investigational Site, New Haven

Sponsors

Lead Sponsor

All Listed Sponsors

lead

Pfizer

INDUSTRY

NCT02097329 - Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And Food | Biotech Hunter | Biotech Hunter