39
Participants
Start Date
March 19, 2014
Primary Completion Date
March 27, 2020
Study Completion Date
March 27, 2020
Regorafenib
"Dose Escalation Group Starting Dose of Regorafenib: 80 mg by mouth once a day for 21 days (5 days on and 2 days off) in a 28 days cycle.~Dose Expansion Group Starting Dose of Regorafenib : MTD from Dose Escalation Group."
Cetuximab
"Dose Escalation Group Starting Dose of Cetuximab: 200 mg/m2 initial dose, then 150 mg/m2 by vein over about 1-2 hours on Days 1, 8, 15, and 22 of each 28 day cycle.~Dose Expansion Group Starting Dose of Cetuximab: MTD from Dose Escalation Group."
Questionnaire
Symptom questionnaire completed at each study visit.
University of Texas MD Anderson Cancer Center, Houston
M.D. Anderson Cancer Center
OTHER