In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation

NACompletedINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

March 31, 2014

Primary Completion Date

June 30, 2015

Study Completion Date

June 30, 2015

Conditions
Respiratory DiseasesLung DiseasesCystic FibrosisCOPDAsthma
Interventions
DRUG

Nebulization of Amikacin during NIV (RR: 15 cycles/minute)

500 mg/4 mL Amikacin nebulized using vibrating mesh nebulizer associated with a single limb bilevel ventilator. The nebulizations are considered as finished when there is no visible evidence of nebulization for a period of 30 seconds. The NIV is set with an IPAP of 15 cmH2O and EPAP of 5 cmH2O. The lung model is simulated with a respiratory rate of 15 cycles/minute

DRUG

Nebulization of Amikacin during NIV (RR: 25 cycles/minute)

500 mg/4 mL Amikacin nebulized using vibrating mesh nebulizer associated with a single limb bilevel ventilator. The nebulizations are considered as finished when there is no visible evidence of nebulization for a period of 30 seconds. The NIV is set with an IPAP of 15 cmH2O and EPAP of 5 cmH2O. The lung model is simulated with a respiratory rate of 25 cycles/minute

Trial Locations (1)

1200

University Hospital St Luc, Brussels

All Listed Sponsors
collaborator

Université Catholique de Louvain

OTHER

collaborator

University of Applied Sciences of Western Switzerland

OTHER

collaborator

School of Gestion and Engineering Vaud, Switzerland

UNKNOWN

lead

University Hospital St Luc, Brussels

OTHER

NCT02084043 - In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation | Biotech Hunter | Biotech Hunter