A Study to Look at Tapentadol Oral Solution in Children and Adolescents in Pain

PHASE3CompletedINTERVENTIONAL
Enrollment

216

Participants

Timeline

Start Date

February 19, 2015

Primary Completion Date

March 3, 2019

Study Completion Date

March 14, 2019

Conditions
Acute Pain
Interventions
DRUG

Tapentadol oral solution 4 mg/mL

"Participants aged 6 months to less than 18 years old with a body weight below 20 kg received tapentadol oral solution 4 mg/mL by mouth every 4 hours for up to 72 hours.~Participants from birth to less than 6 months received tapentadol oral solution, diluted 4 fold."

DRUG

Tapentadol oral solution 20 mg/mL

Participants aged from 6 months to less than 18 years with a body weight greater than or equal to 20 kg received tapentadol oral solution 20 mg/mL by mouth every 4 hours for up to 72 hours.

OTHER

Placebo

Matching placebo oral solution was administered by mouth every 4 hours up to 72 hours.

Trial Locations (43)

600

BG002, Stara Zagora

1094

HU004, Budapest

1606

BG005, Sofia

4032

HU003, Debrecen

5800

BG003, Pleven

8950

ES002, Barcelona

10000

HR001, Zagreb

10461

US001, The Bronx

10467

US018, The Bronx

14059

CZ001, Praha 4 - Krč

15224

US014, Pittsburgh

15706

ES009, Santiago de Compostela

19104

US015, Philadelphia

21000

HR003, Split

27710

US006, Durham

28040

ES005, Madrid

28046

ES007, Madrid

33136

US011, Miami

38700

FR002, La Tronche

40202

US012, Louisville

45229

US016, Cincinnati

47003

ES006, Valladolid

53226

US007, Milwaukee

59037

FR001, Lille

72202

US008, Little Rock

73506

CZ004, Fryštát

75235

US003, Dallas

77030

US005, Houston

77900

CZ003, Olomouc

79106

DE001, Freiburg im Breisgau

87000

FR004, Limoges

94305

US004, Stanford

85-094

PL011, Bydgoszcz

80-803

PL010, Gdansk

93-338

PL005, Lodz

20-093

PL002, Lublin

10-561

PL009, Olsztyn

35-301

PL014, Rzeszów

87-100

PL007, Torun

04-730

PL004, Warsaw

PL008, Warsaw

BS2 8BJ

GB003, Bristol

S10 2TH

GB001, Sheffield

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Depomed

INDUSTRY

lead

Grünenthal GmbH

INDUSTRY