NCT02080819View on ClinicalTrials.gov

Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse

PHASE2CompletedINTERVENTIONAL
Enrollment

131

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

January 21, 2017

Study Completion Date

January 21, 2017

Conditions
Cocaine Dependence
Interventions
DRUG

levodopa/carbidopa 400/100 BID

"Levodopa dose escalation (1 week): Days 1-2, one 50/12.5 mg tablet BID; Days 3-4, one 100/25 mg tablet BID; Days 5-6, one 200/50 mg tablet BID; Day 7, one 400/100 mg tablet BID.~Maintenance phase (7 weeks): One 400/100 mg Levodopa/Carbidopa tablet BID or placebo in conjunction with once weekly individual cognitive behavioral therapy plus contingency management for attendance."

Trial Locations (1)

23298

Virginia Commonwealth University, Richmond

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Virginia Commonwealth University

OTHER

NCT02080819 - Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse | Biotech Hunter | Biotech Hunter