A Study Of PF-06647263 In Patients With Advanced Solid Tumors

PHASE1TerminatedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 9, 2014

Primary Completion Date

May 10, 2017

Study Completion Date

May 10, 2017

Conditions
NeoplasmsTriple-Negative Breast Cancer
Interventions
DRUG

PF-06647263

Part 1- PF-06647263 will be administered intravenously in either a 21 day cycle or weekly in cohorts of 2 or more patients starting at a dose of 0.015 mg/kg. Increases in dose will continue until MTD is determined.

DRUG

PF-06647263

Part 2- Patients with triple negative breast cancer will be treated at the MTD or Recommended Phase 2 dose selected in Part 1.

Trial Locations (10)

37203

Sarah Cannon Research Institute, Nashville

Tennessee Oncology, PLLC, Nashville

48201

Karmanos Cancer Institute, Detroit

77030

The University of Texas MD Anderson Cancer Center, Houston

84112

Huntsman Cancer Hospital / University of Utah, Salt Lake City

Huntsman Cancer Institute-University of Utah, Salt Lake City

89169

Comprehensive Cancer Centers Of Nevada, Las Vegas

02114

Massachusetts General Hospital, Boston

02115

Brigham & Women's Hospital (BWH), Boston

02215

Dana-Farber Cancer Institute (DFCI), Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT02078752 - A Study Of PF-06647263 In Patients With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter