Study of the Glutaminase Inhibitor CB-839 in Hematological Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

April 30, 2016

Study Completion Date

April 30, 2016

Conditions
Non-Hodgkin's Lymphoma (NHL)Multiple MyelomaWaldenstrom's Macroglobulinemia (WM)Other B-cell NHL Subtypes, Including WMT-cell NHL
Interventions
DRUG

CB-839

Glutaminase inhibitor

DRUG

CB-839 and low dose dexamethasone

CB-839 and low dose dexamethasone

DRUG

CB-839, pomalidomide, and low dose dexamethasone

CB-839, pomalidomide, and low dose dexamethasone

Trial Locations (7)

10065

Weill Cornell Medical College, New York

19104

University of Pennsylvania, Abramson Cancer Center, Philadelphia

30322

Winship Cancer Institute of Emory School of Medicine, Atlanta

37203

Tennessee Oncology, PLLC, Nashville

80218

Colorado Blood Cancer Institute, Denver

85259-5499

Mayo Clinic, Scottsdale

07601

John Theruer Cancer Center at Hackensack University Medical Center, Hackensack

Sponsors
All Listed Sponsors
lead

Calithera Biosciences, Inc

INDUSTRY