Cannabinoid Control of Fear Extinction Neural Circuits in Post-traumatic Stress Disorder

NACompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

November 30, 2014

Primary Completion Date

December 31, 2019

Study Completion Date

December 31, 2019

Conditions
Post-Traumatic Stress Disorder
Interventions
DRUG

Dronabinol

Dronabinol (7.5mg) is administered only once (approximately 120 min prior to fMRI scanning in Visit 3) by the oral route and is placed in opaque capsules with dextrose filler. Half of the participants in each diagnostic group \[HC = 20; PTSD = 20; TEC = 20\] will receive dronabinol.

DRUG

Placebo

Placebo is administered only once (approximately 120 min prior to fMRI scanning in Visit 3) by the oral route and contains only dextrose in opaque capsules. Half of the participants in each diagnostic group \[HC = 20; PTSD = 20; TEC = 20\] will receive placebo.

Trial Locations (1)

48201

Eugene Applebaum College of Pharmacy and Health Sciences, Detroit

All Listed Sponsors
lead

Wayne State University

OTHER

NCT02069366 - Cannabinoid Control of Fear Extinction Neural Circuits in Post-traumatic Stress Disorder | Biotech Hunter | Biotech Hunter